Phenolic Compound, Triterpene and Steroids From The Leaves and Bark of Dysoxylum Macrocarpum

Main Article Content

Ibrahim A. Najmuldeen
Kamal Aziz Ketuly
A. Hamid A. Hadi

Abstract

The bark and leaves of Dysoxylum macrocarpum (Meliaceace) yielded four compounds, two compounds from the leaves; 5-hydroxy-7-methoxy-2-methyl-4H-chromen-4-one (Eugenin) DM1, which was new as crystal and squalene DM2, while two more compounds were found from the bark; stigmasterol DM3 and sitosterol DM4.


The present work involves extraction, isolation and purification of compounds by using column chromatography followed by preparative TLC. Structural elucidation has been done through several spectroscopic methods, notably UV, IR, MS (HRMS, GCMS, and LCMS), 1D, 2D-NMR 1H NMR, 13CNMR, COSY, DEPT, HMQC, HMBC, and single crystal X-ray diffraction analysis.

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Article Details

Section

Science Journal of University of Zakho

Author Biographies

Ibrahim A. Najmuldeen, University of Zakho

Department of Chemistry, Faculty of Science, University of Zakho, Zakho, Kurdistan Region, Iraq.

Kamal Aziz Ketuly, University of Duhok

Department of Biochemistry, Faculty of Medicine, University of Dohuk, Dohuk, Kurdistan Region, Iraq

A. Hamid A. Hadi, University of Malaya

Department of chemistry, Faculty of science, University Malaya, 50603 Kuala Lumpur, Malaysia

How to Cite

Najmuldeen, I. A., Ketuly, K. A., & Hadi, A. H. A. (2013). Phenolic Compound, Triterpene and Steroids From The Leaves and Bark of Dysoxylum Macrocarpum. Science Journal of University of Zakho, 1(1), 227-245. https://www.stest.uoz.edu.krd/index.php/sjuoz/article/view/79